Phytochemical Screening And Antibacterial Activity Of Aqueous Extracts Of Citrullus Colocynthis Seeds

Skin, gynecological and lung infections are caused by microorganisms exist in the world. The treatment of these infections is mainly based on the use of synthetic drugs that become, in recent years, ineffective, due to the resistance of bacterial strains and the proliferation of opportunistic fungi. The aim of this study is to test in vitro the antibacterial activity of aqueous extract from seeds of Citrullus colocynthis which was detected phytochemical families existing. These antimicrobial powers are measured using the micro-dilution method against the Gram-negative bacteria (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) and Gram-positive (Enterococcus faecalis ATCC 29212 and Staphylococcus aureus ATCC 25923). The results showed that seeds of C. colocynthis are rich by bioactive substances. All tested extracts of C. colocynthis showed antimicrobial activity against all strains tested.. The folk medicinal use as a broad-spectrum antimicrobial agent is validated.