This work aims at evaluating the anti-inflammatory activity of an endemic species ofthe central sahara: MyrtusnivelleiBatt&Trab. The methanolic extract of this plant was extracted by Soxhlet apparatus and concentrated under reduced pressure using a rotary evaporator.
In the carrageenan-induced paw edematest, five different groups of mice were established and the extract was administered orally in three different doses. The dose of 400 mg/kg was able to reduce significantly the paw edema with a comparable effect to that observed with Diclofenac (positive control).This is the first report to demonstrate a significant anti-inflammatory activity of the methanolic extract prepared from Myrtusnivellei.
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Posté Le : 04/05/2022
Posté par : einstein
Ecrit par : - Touaibia M. - Chaouch F.z.
Source : Revue des Sciences Fondamentales Appliquées Volume 7, Numéro 1, Pages 77-8278 2015-01-01