In the present study, the protective effect of an aqueous extract of green tea (GTE) against renal oxidative damage
induced by lead was undertaken. Adult males rats were divided into 4 groups: Control group receives distilled water
as sole drinking source. GTE group received green tea extract (6.6% w/v).Pb group received Pb at dose of 0.4 %
w/v in distilled water. Pb + GTE group received mixture of Pb and GTE as sole drinking source. Renal oxidative
damage was observed in Pb-treated rats as evidenced via augmentation in kidney lipid peroxidation (LPO) as well
as depletion in kidney antioxidant enzymes; catalase (CAT), superoxide dismutase (SOD) and glutathione
peroxidase (GPx). Histopathological analysis revealed degeneration in the endothelium of glomerular tuft and the
epithelium of lining tubules. In conclusion, GTE appeared to be beneficial to rats, to a great extent by attenuating
and restoring the damage sustained by lead exposure.
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Posté Le : 17/09/2023
Posté par : einstein
Ecrit par : - Ait Hamadouche Nadia - Lazeb Hadjira - Kaddouri Assia - Guellil Hayet - Slimani Miloud - Aoues Abdelkader
Source : Algerian Journal of Natural Products Volume 3, Numéro 1, Pages 130-137 2015-02-10